3EG3
Crystal structure of the N114A mutant of ABL-SH3 domain
Summary for 3EG3
Entry DOI | 10.2210/pdb3eg3/pdb |
Related | 1BBZ 2O88 3EG0 3EG1 3EG2 |
Descriptor | Proto-oncogene tyrosine-protein kinase ABL1, GLYCEROL (3 entities in total) |
Functional Keywords | beta, atp-binding, cell adhesion, cytoskeleton, kinase, lipoprotein, magnesium, manganese, metal-binding, myristate, nucleotide-binding, nucleus, phosphoprotein, proto-oncogene, sh2 domain, sh3 domain, transferase, tyrosine-protein kinase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, cytoskeleton. Isoform IB: Nucleus membrane; Lipid-anchor: P00519 |
Total number of polymer chains | 1 |
Total formula weight | 7058.76 |
Authors | Camara-Artigas, A. (deposition date: 2008-09-10, release date: 2009-09-15, Last modification date: 2023-08-30) |
Primary citation | Palencia, A.,Camara-Artigas, A.,Pisabarro, M.T.,Martinez, J.C.,Luque, I. Role of interfacial water molecules in proline-rich ligand recognition by the Src homology 3 domain of Abl. J.Biol.Chem., 285:2823-2833, 2010 Cited by PubMed: 19906645DOI: 10.1074/jbc.M109.048033 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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