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3EG2

Crystal structure of the N114Q mutant of ABL-SH3 domain

Summary for 3EG2
Entry DOI10.2210/pdb3eg2/pdb
Related1bbz 2o88 3EG0 3EG1 3EG3
DescriptorProto-oncogene tyrosine-protein kinase ABL1, GLYCEROL (3 entities in total)
Functional Keywordsbeta, atp-binding, cell adhesion, cytoskeleton, kinase, lipoprotein, magnesium, manganese, metal-binding, myristate, nucleotide-binding, nucleus, phosphoprotein, proto-oncogene, sh2 domain, sh3 domain, transferase, tyrosine-protein kinase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm, cytoskeleton. Isoform IB: Nucleus membrane; Lipid-anchor: P00519
Total number of polymer chains1
Total formula weight7115.81
Authors
Camara-Artigas, A. (deposition date: 2008-09-10, release date: 2009-09-15, Last modification date: 2023-08-30)
Primary citationPalencia, A.,Camara-Artigas, A.,Pisabarro, M.T.,Martinez, J.C.,Luque, I.
Role of interfacial water molecules in proline-rich ligand recognition by the Src homology 3 domain of Abl.
J.Biol.Chem., 285:2823-2833, 2010
Cited by
PubMed: 19906645
DOI: 10.1074/jbc.M109.048033
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

217705

건을2024-03-27부터공개중

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