3EE6

Crystal Structure Analysis of Tripeptidyl peptidase -I

Summary for 3EE6

Entry DOI	10.2210/pdb3ee6/pdb
Descriptor	Tripeptidyl-peptidase 1, 2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... (7 entities in total)
Functional Keywords	tripepetidyl peptidase -i, disease mutation, epilepsy, glycoprotein, hydrolase, lysosome, neuronal ceroid lipofuscinosis, protease, serine protease, zymogen
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	127389.69
Authors	Pal, A.,Kraetzner, R.,Grapp, M.,Gruene, T.,Schreiber, K.,Granborg, M.,Urlaub, H.,Asif, A.R.,Becker, S.,Gartner, J.,Sheldrick, G.M.,Steinfeld, R. (deposition date: 2008-09-04, release date: 2008-11-25, Last modification date: 2020-07-29)
Primary citation	Pal, A.,Kraetzner, R.,Gruene, T.,Grapp, M.,Schreiber, K.,Gronborg, M.,Urlaub, H.,Becker, S.,Asif, A.R.,Gartner, J.,Sheldrick, G.M.,Steinfeld, R. Structure of tripeptidyl-peptidase I provides insight into the molecular basis of late infantile neuronal ceroid lipofuscinosis J.Biol.Chem., 284:3976-3984, 2009 Cited by PubMed: 19038966 DOI: 10.1074/jbc.M806947200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.35 Å)

Structure validation