3EA1

Crystal Structure of the Y247S/Y251S Mutant of Phosphatidylinositol-Specific Phospholipase C from Bacillus Thuringiensis

Summary for 3EA1

Entry DOI	10.2210/pdb3ea1/pdb
Related	3EA2 3EA3
Descriptor	1-phosphatidylinositol phosphodiesterase, ZINC ION (3 entities in total)
Functional Keywords	phosphatidylinositol-specific phospholipase c, pi-plc, dimer, interfacially impaired, membrane binding, tim barrel, lipid degradation, lyase, secreted
Biological source	Bacillus thuringiensis
Cellular location	Secreted: P08954
Total number of polymer chains	2
Total formula weight	69187.17
Authors	Shi, X.,Shao, C.,Zhang, X.,Zambonelli, C.,Redfied, A.G.,Head, J.F.,Seaton, B.A.,Roberts, M.F. (deposition date: 2008-08-24, release date: 2009-04-14, Last modification date: 2024-02-21)
Primary citation	Shi, X.,Shao, C.,Zhang, X.,Zambonelli, C.,Redfield, A.G.,Head, J.F.,Seaton, B.A.,Roberts, M.F. Modulation of bacillus thuringiensis phosphatidylinositol-specific phospholipase C activity by mutations in the putative dimerization interface. J.Biol.Chem., 284:15607-15618, 2009 Cited by PubMed: 19369255 DOI: 10.1074/jbc.M901601200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation