3E9K

Crystal structure of Homo sapiens kynureninase-3-hydroxyhippuric acid inhibitor complex

3E9K の概要

• エントリーDOI: 10.2210/pdb3e9k/pdb
• 関連するPDBエントリー: 1QZ9 2HZP
• 分子名称: Kynureninase, PYRIDOXAL-5'-PHOSPHATE, 3-Hydroxyhippuric acid, ... (4 entities in total)
• 機能のキーワード: kynureninase, kynurenine-l-hydrolase, kynurenine hydrolase, pyridoxal-5'-phosphate, inhibitor complex, 3-hydroxy hippurate, 3-hydroxyhippuric acid, plp, pyridine nucleotide biosynthesis, pyridoxal phosphate, hydrolase
• 由来する生物種: Homo sapiens
• 細胞内の位置: Cytoplasm: Q16719
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 52882.78

構造登録者

Lima, S.,Kumar, S.,Gawandi, V.,Momany, C.,Phillips, R.S. (登録日: 2008-08-22, 公開日: 2008-12-09, 最終更新日: 2023-08-30)

• 主引用文献: Lima, S.,Kumar, S.,Gawandi, V.,Momany, C.,Phillips, R.S.; Crystal structure of the Homo sapiens kynureninase-3-hydroxyhippuric acid inhibitor complex: insights into the molecular basis of kynureninase substrate specificity.; J.Med.Chem., 52:389-396, 2009; PubMed: 19143568; DOI: 10.1021/jm8010806

実験手法

X-RAY DIFFRACTION (1.7 Å)