3E8U

Crystal structure and thermodynamic analysis of diagnostic Fab 106.3 complexed with BNP 5-13 (C10A) reveal basis of selective molecular recognition

Summary for 3E8U

• Entry DOI: 10.2210/pdb3e8u/pdb
• Descriptor: Fab 106.3 heavy chain, Fab 106.3 light chain, BNP peptide epitope, ... (4 entities in total)
• Functional Keywords: fab 106.3, igg1, brain natriuretic peptide (bnp), immune system
• Biological source: Mus musculus; More
• Total number of polymer chains: 3
• Total formula weight: 48149.18

Authors

Longenecker, K.L.,Ruan, Q.,Fry, E.H.,Saldana, S.S.,Brophy, S.E.,Richardson, P.L.,Tetin, S.Y. (deposition date: 2008-08-20, release date: 2009-07-07, Last modification date: 2017-10-25)

• Primary citation: Longenecker, K.L.,Ruan, Q.,Fry, E.H.,Saldana, S.C.,Brophy, S.E.,Richardson, P.L.,Tetin, S.Y.; Crystal structure and thermodynamic analysis of diagnostic mAb 106.3 complexed with BNP 5-13 (C10A).; Proteins, 76:536-547, 2009; PubMed: 19274732; DOI: 10.1002/prot.22366

Experimental method

X-RAY DIFFRACTION (2.1 Å)