3E6V

X-ray structure of human arginase I-D183N mutant: the complex with ABH

3E6V の概要

• エントリーDOI: 10.2210/pdb3e6v/pdb
• 関連するPDBエントリー: 2AEB 3E6K
• 分子名称: Arginase-1, MANGANESE (II) ION, 2(S)-AMINO-6-BORONOHEXANOIC ACID, ... (4 entities in total)
• 機能のキーワード: amino acid recognition, mutant, amino group recognition, alternative splicing, arginine metabolism, cytoplasm, disease mutation, hydrolase, manganese, metal-binding, phosphoprotein, polymorphism, urea cycle
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Cytoplasm: P05089
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 70161.54

構造登録者

Di Costanzo, L.,Christianson, D.W. (登録日: 2008-08-16, 公開日: 2008-12-02, 最終更新日: 2023-08-30)

• 主引用文献: Shishova, E.Y.,Di Costanzo, L.,Emig, F.A.,Ash, D.E.,Christianson, D.W.; Probing the specificity determinants of amino acid recognition by arginase.; Biochemistry, 48:121-131, 2009; PubMed: 19093830; DOI: 10.1021/bi801911v

実験手法

X-RAY DIFFRACTION (1.72 Å)