3DWQ
Crystal structure of the A-subunit of the AB5 toxin from E. coli with Neu5Gc-2,3Gal-1,3GlcNAc
Summary for 3DWQ
Entry DOI | 10.2210/pdb3dwq/pdb |
Related | 3dwa 3dwp |
Descriptor | Subtilase cytotoxin, subunit B, N-glycolyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, N-PROPANOL, ... (6 entities in total) |
Functional Keywords | toxin |
Biological source | Escherichia coli |
Total number of polymer chains | 5 |
Total formula weight | 74530.25 |
Authors | Byres, E.,Paton, A.W.,Paton, J.C.,Lofling, J.C.,Smith, D.F.,Wilce, M.C.J.,Talbot, U.M.,Chong, D.C.,Yu, H.,Huang, S.,Chen, X.,Varki, N.M.,Varki, A.,Rossjohn, J.,Beddoe, T. (deposition date: 2008-07-22, release date: 2008-11-04, Last modification date: 2020-07-29) |
Primary citation | Byres, E.,Paton, A.W.,Paton, J.C.,Lofling, J.C.,Smith, D.F.,Wilce, M.C.J.,Talbot, U.M.,Chong, D.C.,Yu, H.,Huang, S.,Chen, X.,Varki, N.M.,Varki, A.,Rossjohn, J.,Beddoe, T. Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin Nature, 456:648-652, 2008 Cited by PubMed: 18971931DOI: 10.1038/nature07428 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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