3DVU

Crystal structure of the complex of murine gamma-herpesvirus 68 Bcl-2 homolog M11 and the Beclin 1 BH3 domain

Summary for 3DVU

• Entry DOI: 10.2210/pdb3dvu/pdb
• Related: 3BL2
• Descriptor: V-bcl-2, Beclin-1 (3 entities in total)
• Functional Keywords: autophagy, protein-protein complex, viral bcl-2, beclin 1, apoptosis, m11, antiviral defense, bh3 domain, coiled coil, cytoplasm, golgi apparatus, membrane, polymorphism, viral protein-apoptosis complex, viral protein/apoptosis
• Biological source: Murid herpesvirus 4 (MuHV-4); More
• Total number of polymer chains: 4
• Total formula weight: 38996.15

Authors

Sinha, S. (deposition date: 2008-07-20, release date: 2008-10-07, Last modification date: 2023-11-01)

• Primary citation: Sinha, S.,Colbert, C.L.,Becker, N.,Wei, Y.,Levine, B.; Molecular basis of the regulation of Beclin 1-dependent autophagy by the gamma-herpesvirus 68 Bcl-2 homolog M11.; Autophagy, 4:989-997, 2008; PubMed: 18797192; DOI: 10.4161/auto.6803

Experimental method

X-RAY DIFFRACTION (2.5 Å)