3DUH

Structure of Interleukin-23

Summary for 3DUH

• Entry DOI: 10.2210/pdb3duh/pdb
• Descriptor: Interleukin-12 subunit beta, Interleukin-23 subunit alpha, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: four-helix bundle cytokine, ig domain, cytokine, glycoprotein, immunoglobulin domain, secreted, antiviral defense, immune response, inflammatory response, innate immunity, tissue remodeling, immune system, immune system-cytokine complex, immune system/cytokine
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 111340.92

Authors

Lupardus, P.J.,Garcia, K.C. (deposition date: 2008-07-17, release date: 2008-08-19, Last modification date: 2023-08-30)

• Primary citation: Lupardus, P.J.,Garcia, K.C.; The structure of interleukin-23 reveals the molecular basis of p40 subunit sharing with interleukin-12.; J.Mol.Biol., 382:931-941, 2008; PubMed: 18680750; DOI: 10.1016/j.jmb.2008.07.051

Experimental method

X-RAY DIFFRACTION (2.3 Å)