3DUH

Structure of Interleukin-23

3DUH の概要

• エントリーDOI: 10.2210/pdb3duh/pdb
• 分子名称: Interleukin-12 subunit beta, Interleukin-23 subunit alpha, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: four-helix bundle cytokine, ig domain, cytokine, glycoprotein, immunoglobulin domain, secreted, antiviral defense, immune response, inflammatory response, innate immunity, tissue remodeling, immune system, immune system-cytokine complex, immune system/cytokine
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 111340.92

構造登録者

Lupardus, P.J.,Garcia, K.C. (登録日: 2008-07-17, 公開日: 2008-08-19, 最終更新日: 2023-08-30)

• 主引用文献: Lupardus, P.J.,Garcia, K.C.; The structure of interleukin-23 reveals the molecular basis of p40 subunit sharing with interleukin-12.; J.Mol.Biol., 382:931-941, 2008; PubMed: 18680750; DOI: 10.1016/j.jmb.2008.07.051

実験手法

X-RAY DIFFRACTION (2.3 Å)