3DSD

Crystal structure of P. furiosus Mre11-H85S bound to a branched DNA and manganese

Summary for 3DSD

• Entry DOI: 10.2210/pdb3dsd/pdb
• Related: 1II7 1s8e 3DSC
• Descriptor: DNA double-strand break repair protein mre11, DNA (5'-D(*DCP*DGP*DCP*DGP*DCP*DAP*DCP*DAP*DAP*DGP*DCP*DTP*DTP*DTP*DTP*DGP*DCP*DTP*DTP*DGP*DTP*DGP*DGP*DAP*DTP*DA)-3'), MANGANESE (II) ION, ... (4 entities in total)
• Functional Keywords: protein-dna complex, double helix, nuclease, dna damage, dna repair, endonuclease, exonuclease, hydrolase, manganese, metal-binding, hydrolase-dna complex, hydrolase/dna
• Biological source: Pyrococcus furiosus
• Total number of polymer chains: 3
• Total formula weight: 89953.08

Authors

Williams, R.S.,Moiani, D.,Tainer, J.A. (deposition date: 2008-07-11, release date: 2008-10-14, Last modification date: 2023-08-30)

• Primary citation: Williams, R.S.,Moncalian, G.,Williams, J.S.,Yamada, Y.,Limbo, O.,Shin, D.S.,Groocock, L.M.,Cahill, D.,Hitomi, C.,Guenther, G.,Moiani, D.,Carney, J.P.,Russell, P.,Tainer, J.A.; Mre11 dimers coordinate DNA end bridging and nuclease processing in double-strand-break repair.; Cell(Cambridge,Mass.), 135:97-109, 2008; PubMed: 18854158; DOI: 10.1016/j.cell.2008.08.017

Experimental method

X-RAY DIFFRACTION (2.2 Å)