3DRO
Crystal structure of the HIV-1 Cross Neutralizing Antibody 2F5 in complex with gp41 Peptide ELLELDKWASLWN grown in ammonium sulfate
Summary for 3DRO
Entry DOI | 10.2210/pdb3dro/pdb |
Related | 2P8M 3DRQ 3DRT 3DRV |
Descriptor | 2F5 Fab light chain, 2F5 Fab heavy chain, ELLELDKWASLWN gp41 peptide (3 entities in total) |
Functional Keywords | hiv-1, gp41, 2f5, nmab, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Host cell membrane ; Single-pass type I membrane protein . Host endosome membrane ; Single-pass type I membrane protein . Virion membrane ; Single-pass type I membrane protein : Q5S532 |
Total number of polymer chains | 3 |
Total formula weight | 49967.10 |
Authors | Julien, J.-P.,Bryson, S.,Pai, E.F. (deposition date: 2008-07-11, release date: 2008-07-29, Last modification date: 2023-08-30) |
Primary citation | Julien, J.P.,Bryson, S.,Nieva, J.L.,Pai, E.F. Structural details of HIV-1 recognition by the broadly neutralizing monoclonal antibody 2F5: epitope conformation, antigen-recognition loop mobility, and anion-binding site. J.Mol.Biol., 384:377-392, 2008 Cited by PubMed: 18824005DOI: 10.1016/j.jmb.2008.09.024 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.9 Å) |
Structure validation
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