3DQB

Crystal structure of the active G-protein-coupled receptor opsin in complex with a C-terminal peptide derived from the Galpha subunit of transducin

3DQB の概要

• エントリーDOI: 10.2210/pdb3dqb/pdb
• 分子名称: Rhodopsin, 11meric peptide form Guanine nucleotide-binding protein G(t) subunit alpha-1, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: protein, retinal protein, photoreceptor, ligand-free state, chromophore, g-protein coupled receptor, glycoprotein, lipoprotein, palmitate, phosphoprotein, photoreceptor protein, sensory transduction, transducer, transmembrane, vision, signaling protein, g-protein, transducin, galpha subunit, membrane, receptor, gtp-binding, myristate, nucleotide-binding, g-protein-coupled receptor, rhodopsin, opsin
• 由来する生物種: Bos taurus (Bovine); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 42859.99

構造登録者

Scheerer, P.,Park, J.H.,Hildebrand, P.W.,Kim, Y.J.,Krauss, N.,Choe, H.-W.,Hofmann, K.P.,Ernst, O.P. (登録日: 2008-07-09, 公開日: 2008-09-23, 最終更新日: 2023-11-01)

• 主引用文献: Scheerer, P.,Park, J.H.,Hildebrand, P.W.,Kim, Y.J.,Krauss, N.,Choe, H.-W.,Hofmann, K.P.,Ernst, O.P.; Crystal structure of opsin in its G-protein-interacting conformation; Nature, 455:497-502, 2008; PubMed: 18818650; DOI: 10.1038/nature07330

実験手法

X-RAY DIFFRACTION (3.2 Å)