3DLS

Crystal structure of human PAS kinase bound to ADP

3DLS の概要

• エントリーDOI: 10.2210/pdb3dls/pdb
• 分子名称: PAS domain-containing serine/threonine-protein kinase, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
• 機能のキーワード: pas kinase, pask, protein kinase, drug discovery, atp-binding, kinase, nucleotide-binding, phosphoprotein, serine/threonine-protein kinase, transferase, structural genomics, psi-2, protein structure initiative, new york sgx research center for structural genomics, nysgxrc
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 230276.62

構造登録者

Antonysamy, S.,Bonanno, J.B.,Romero, R.,Russell, M.,Iizuka, M.,Gheyi, T.,Wasserman, S.R.,Rutter, J.,Sauder, J.M.,Burley, S.K.,New York SGX Research Center for Structural Genomics (NYSGXRC) (登録日: 2008-06-29, 公開日: 2008-08-26, 最終更新日: 2024-02-21)

• 主引用文献: Kikani, C.K.,Antonysamy, S.A.,Bonanno, J.B.,Romero, R.,Zhang, F.F.,Russell, M.,Gheyi, T.,Iizuka, M.,Emtage, S.,Sauder, J.M.,Turk, B.E.,Burley, S.K.,Rutter, J.; Structural bases of PAS domain-regulated kinase (PASK) activation in the absence of activation loop phosphorylation.; J.Biol.Chem., 285:41034-41043, 2010; PubMed: 20943661; DOI: 10.1074/jbc.M110.157594

実験手法

X-RAY DIFFRACTION (2.3 Å)