3DKO

Complex between the kinase domain of human ephrin type-a receptor 7 (epha7) and inhibitor alw-ii-49-7

3DKO の概要

• エントリーDOI: 10.2210/pdb3dko/pdb
• 関連するPDBエントリー: 2REI
• 分子名称: Ephrin type-A receptor 7, 5-[(2-methyl-5-{[3-(trifluoromethyl)phenyl]carbamoyl}phenyl)amino]pyridine-3-carboxamide (3 entities in total)
• 機能のキーワード: atp-binding, kinase, nucleotide-binding, receptor, transferase, phosphorylation, transmembrane, tyrosine-protein kinase, alternative splicing, glycoprotein, inhibitor, structural genomics consortium, sgc, membrane, phosphoprotein, polymorphism, nppsfa, national project on protein structural and functional analyses
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Cell membrane ; Single-pass type I membrane protein : Q15375
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 36653.91

構造登録者

Walker, J.R.,Syeda, F.,Gray, N.,Butler-Cole, C.,Bountra, C.,Wolkstrom, M.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Dhe-Paganon, S.,Structural Genomics Consortium (SGC) (登録日: 2008-06-25, 公開日: 2008-08-19, 最終更新日: 2023-08-30)

• 主引用文献: Walker, J.R.,Syeda, F.,Gray, N.,Butler-Cole, C.,Bountra, C.,Wolkstrom, M.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Dhe-Paganon, S.; Kinase domain of human ephrin type-a receptor 7 (epha7) in complex with ALW-II-49-7; To be Published,

実験手法

X-RAY DIFFRACTION (2 Å)