3DJO

Bovine Seminal Ribonuclease uridine 2' phosphate complex

3DJO の概要

• エントリーDOI: 10.2210/pdb3djo/pdb
• 関連するPDBエントリー: 3DJP 3DJQ 3DJV 3DJX
• 分子名称: Seminal ribonuclease, PHOSPHORIC ACID MONO-[2-(2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-4-HYDROXY-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3-YL] ESTER, ACETATE ION, ... (4 entities in total)
• 機能のキーワード: ribonuclease, hydrolase, allosteric enzyme, endonuclease, nuclease, secreted
• 由来する生物種: Bos taurus (Bovine)
• 細胞内の位置: Secreted: P00669
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 28031.73

構造登録者

Dossi, K.,Leonidas, D.D.,Zographos, S.E.,Oikonomakos, N.G. (登録日: 2008-06-24, 公開日: 2009-06-30, 最終更新日: 2023-11-01)

• 主引用文献: Dossi, K.,Tsirkone, V.G.,Hayes, J.M.,Matousek, J.,Pouckova, P.,Soucek, J.,Zadinova, M.,Zographos, S.E.,Leonidas, D.D.; Mapping the ribonucleolytic active site of bovine seminal ribonuclease. The binding of pyrimidinyl phosphonucleotide inhibitors; Eur.J.Med.Chem., 44:4496-4508, 2009; PubMed: 19643512; DOI: 10.1016/j.ejmech.2009.06.039

実験手法

X-RAY DIFFRACTION (1.6 Å)