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3DJK

Wild Type HIV-1 Protease with potent Antiviral inhibitor GRL-0255A

3DJK の概要
エントリーDOI10.2210/pdb3djk/pdb
関連するPDBエントリー2HB3 2IEN 2Z4O 3DK1
分子名称Protease, SODIUM ION, CHLORIDE ION, ... (5 entities in total)
機能のキーワードhiv-1, wild type protease, protease inhibitor, hydrolase, aids, aspartyl protease, capsid maturation, capsid protein, cytoplasm, dna integration, dna recombination, dna-directed dna polymerase, endonuclease, lipoprotein, magnesium, metal-binding, multifunctional enzyme, myristate, nuclease, nucleotidyltransferase, nucleus, phosphoprotein, protease, ribosomal frameshifting, rna-binding, rna-directed dna polymerase, transferase, viral nucleoprotein, virion, zinc, zinc-finger
由来する生物種Human immunodeficiency virus type 1 (HIV-1)
細胞内の位置Gag-Pol polyprotein: Host cell membrane ; Lipid-anchor. Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion . Reverse transcriptase/ribonuclease H: Virion . Integrase: Virion : P03367
タンパク質・核酸の鎖数2
化学式量合計22184.36
構造登録者
Wang, Y.F.,Weber, I.T. (登録日: 2008-06-23, 公開日: 2008-09-30, 最終更新日: 2023-11-01)
主引用文献Ghosh, A.K.,Gemma, S.,Baldridge, A.,Wang, Y.F.,Kovalevsky, A.Y.,Koh, Y.,Weber, I.T.,Mitsuya, H.
Flexible cyclic ethers/polyethers as novel P2-ligands for HIV-1 protease inhibitors: design, synthesis, biological evaluation, and protein-ligand X-ray studies
J.Med.Chem., 51:6021-6033, 2008
Cited by
PubMed: 18783203
DOI: 10.1021/jm8004543
主引用文献が同じPDBエントリー
実験手法
X-RAY DIFFRACTION (1 Å)
構造検証レポート
Validation report summary of 3djk
検証レポート(詳細版)ダウンロードをダウンロード

222415

件を2024-07-10に公開中

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