3DGB

Crystal structure of muconate lactonizing enzyme from Pseudomonas Fluorescens complexed with muconolactone

Summary for 3DGB

• Entry DOI: 10.2210/pdb3dgb/pdb
• Related: 3CT2 3FJ4
• Descriptor: Muconate cycloisomerase, MAGNESIUM ION, [(2S)-5-oxo-2,5-dihydrofuran-2-yl]acetic acid, ... (4 entities in total)
• Functional Keywords: muconate lactonizing enzyme, muconolactone binding, isomerase, structural genomics, psi-2, protein structure initiative, new york sgx research center for structural genomics, nysgxrc
• Biological source: Pseudomonas fluorescens
• Total number of polymer chains: 1
• Total formula weight: 41218.35

Authors

Fedorov, A.A.,Fedorov, E.V.,Sauder, J.M.,Burley, S.K.,Gerlt, J.A.,Almo, S.C.,New York SGX Research Center for Structural Genomics (NYSGXRC) (deposition date: 2008-06-13, release date: 2009-03-03, Last modification date: 2024-03-20)

• Primary citation: Sakai, A.,Fedorov, A.A.,Fedorov, E.V.,Schnoes, A.M.,Glasner, M.E.,Brown, S.,Rutter, M.E.,Bain, K.,Chang, S.,Gheyi, T.,Sauder, J.M.,Burley, S.K.,Babbitt, P.C.,Almo, S.C.,Gerlt, J.A.; Evolution of enzymatic activities in the enolase superfamily: stereochemically distinct mechanisms in two families of cis,cis-muconate lactonizing enzymes; Biochemistry, 48:1445-1453, 2009; PubMed: 19220063; DOI: 10.1021/bi802277h

Experimental method

X-RAY DIFFRACTION (1.7 Å)