3DF0

Calcium-dependent complex between m-calpain and calpastatin

3DF0 の概要

• エントリーDOI: 10.2210/pdb3df0/pdb
• 分子名称: Calpain-2 catalytic subunit, Calpain small subunit 1, Calpastatin, ... (4 entities in total)
• 機能のキーワード: protease core domain, penta ef-hand domains, c2-like domain, inhibitor loop-out, hydrolase, membrane, protease, thiol protease, phosphoprotein, protease inhibitor, thiol protease inhibitor
• 由来する生物種: Rattus norvegicus (Rat); 詳細
• 細胞内の位置: Cytoplasm : Q07009 Q64537
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 112562.88

構造登録者

Moldoveanu, T.,Gehring, K.,Green, D.R. (登録日: 2008-06-11, 公開日: 2008-11-11, 最終更新日: 2023-08-30)

• 主引用文献: Moldoveanu, T.,Gehring, K.,Green, D.R.; Concerted multi-pronged attack by calpastatin to occlude the catalytic cleft of heterodimeric calpains.; Nature, 456:404-408, 2008; PubMed: 19020622; DOI: 10.1038/nature07353

実験手法

X-RAY DIFFRACTION (2.95 Å)