3DAR

Crystal structure of D2 domain from human FGFR2

Summary for 3DAR

• Entry DOI: 10.2210/pdb3dar/pdb
• Related: 1E0O 1WVZ
• Descriptor: Fibroblast growth factor receptor 2 (2 entities in total)
• Functional Keywords: immunoglobulin fold, atp-binding, craniosynostosis, disease mutation, ectodermal dysplasia, glycoprotein, heparin-binding, immunoglobulin domain, kinase, lacrimo-auriculo-dento-digital syndrome, membrane, nucleotide-binding, phosphoprotein, receptor, secreted, transferase, transmembrane, tyrosine-protein kinase
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane; Single-pass type I membrane protein. Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 3: Cell membrane; Single-pass type I membrane protein. Isoform 14: Secreted. Isoform 19: Secreted: P21802
• Total number of polymer chains: 2
• Total formula weight: 24367.71

Authors

Brown, A.,Blundell, T.L. (deposition date: 2008-05-30, release date: 2008-06-10, Last modification date: 2023-08-30)

• Primary citation: Brown, A.,Blundell, T.L.; Crystal structure of the FGFR2 D2 domain; To be Published,

Experimental method

X-RAY DIFFRACTION (2.2 Å)