3DAR

Crystal structure of D2 domain from human FGFR2

3DAR の概要

• エントリーDOI: 10.2210/pdb3dar/pdb
• 関連するPDBエントリー: 1E0O 1WVZ
• 分子名称: Fibroblast growth factor receptor 2 (2 entities in total)
• 機能のキーワード: immunoglobulin fold, atp-binding, craniosynostosis, disease mutation, ectodermal dysplasia, glycoprotein, heparin-binding, immunoglobulin domain, kinase, lacrimo-auriculo-dento-digital syndrome, membrane, nucleotide-binding, phosphoprotein, receptor, secreted, transferase, transmembrane, tyrosine-protein kinase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cell membrane; Single-pass type I membrane protein. Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 3: Cell membrane; Single-pass type I membrane protein. Isoform 14: Secreted. Isoform 19: Secreted: P21802
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 24367.71

構造登録者

Brown, A.,Blundell, T.L. (登録日: 2008-05-30, 公開日: 2008-06-10, 最終更新日: 2023-08-30)

• 主引用文献: Brown, A.,Blundell, T.L.; Crystal structure of the FGFR2 D2 domain; To be Published,

実験手法

X-RAY DIFFRACTION (2.2 Å)