3D7M

Crystal Structure of the G Protein Fast-Exchange Double Mutant I56C/Q333C

3D7M の概要

• エントリーDOI: 10.2210/pdb3d7m/pdb
• 関連するPDBエントリー: 1BH2 1GFI 1Y3A 2G83 2HLB
• 分子名称: Guanine nucleotide-binding protein G(i), alpha-1 subunit, MAGNESIUM ION, TETRAFLUOROALUMINATE ION, ... (5 entities in total)
• 機能のキーワード: nucleotide binding, allosteric, gtp-binding, lipoprotein, myristate, nucleotide-binding, palmitate, transducer, signaling protein
• 由来する生物種: Rattus norvegicus (rat)
• 細胞内の位置: Nucleus: P10824
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 40934.51

構造登録者

Funk, M.A.,Preininger, A.M.,Oldham, W.M.,Meier, S.M.,Hamm, H.E.,Iverson, T.M. (登録日: 2008-05-21, 公開日: 2009-03-03, 最終更新日: 2023-08-30)

• 主引用文献: Preininger, A.M.,Funk, M.A.,Oldham, W.M.,Meier, S.M.,Johnston, C.A.,Adhikary, S.,Kimple, A.J.,Siderovski, D.P.,Hamm, H.E.,Iverson, T.M.; Helix dipole movement and conformational variability contribute to allosteric GDP release in Galphai subunits.; Biochemistry, 48:2630-2642, 2009; PubMed: 19222191; DOI: 10.1021/bi801853a

実験手法

X-RAY DIFFRACTION (2.9 Å)