3D5R
Crystal Structure of Efb-C (N138A) / C3d Complex
3D5R の概要
エントリーDOI | 10.2210/pdb3d5r/pdb |
関連するPDBエントリー | 2GOM 2GOX 2NOJ 3D5S |
分子名称 | Complement C3, Fibrinogen-binding protein (3 entities in total) |
機能のキーワード | protein-protein complex, cell adhesion-toxin complex, site-directed mutation, age-related macular degeneration, cleavage on pair of basic residues, complement alternate pathway, complement pathway, disease mutation, glycoprotein, immune response, inflammatory response, innate immunity, phosphoprotein, polymorphism, secreted, thioester bond, cell adhesion/toxin |
由来する生物種 | Homo sapiens (human) 詳細 |
細胞内の位置 | Secreted: P01024 A6QG59 |
タンパク質・核酸の鎖数 | 4 |
化学式量合計 | 81387.51 |
構造登録者 | |
主引用文献 | Haspel, N.,Ricklin, D.,Geisbrecht, B.V.,Kavraki, L.E.,Lambris, J.D. Electrostatic contributions drive the interaction between Staphylococcus aureus protein Efb-C and its complement target C3d. Protein Sci., 17:1894-1906, 2008 Cited by PubMed: 18687868DOI: 10.1110/ps.036624.108 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.1 Å) |
構造検証レポート
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