3D2W
Crystal structure of mouse TDP-43 RRM2 domain in complex with DNA
Summary for 3D2W
| Entry DOI | 10.2210/pdb3d2w/pdb |
| Descriptor | TAR DNA-binding protein 43, DNA (5'-D(*DGP*DTP*DTP*DGP*DAP*DGP*DCP*DGP*DTP*DT)-3'), PHOSPHATE ION, ... (4 entities in total) |
| Functional Keywords | dp-43 proteinopathy, tdp-43 inclusions, rna recognition motif, ftld-u, als, rrm, dna-rna binding protein complex, dna/rna binding protein |
| Biological source | Mus musculus (mouse) More |
| Cellular location | Nucleus (By similarity): Q921F2 |
| Total number of polymer chains | 2 |
| Total formula weight | 13283.46 |
| Authors | Kuo, P.H.,Yuan, H.S. (deposition date: 2008-05-09, release date: 2009-04-07, Last modification date: 2023-11-01) |
| Primary citation | Kuo, P.H.,Doudeva, L.G.,Wang, Y.T.,Shen, C.K.,Yuan, H.S. Structural insights into TDP-43 in nucleic-acid binding and domain interactions Nucleic Acids Res., 37:1799-1808, 2009 Cited by PubMed: 19174564DOI: 10.1093/nar/gkp013 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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