3D29

Proteasome Inhibition by Fellutamide B

3D29 の概要

• エントリーDOI: 10.2210/pdb3d29/pdb
• 関連するPDBエントリー: 1ryp
• 分子名称: PRE8 isoform 1, Proteasome subunit beta, proteasome endopeptidase complex, ... (17 entities in total)
• 機能のキーワード: anti-parallel beta-sheet structure flanked by alpha-helices, cytoplasm, hydrolase, nucleus, protease, proteasome, threonine protease, ubl conjugation, phosphoprotein, zymogen
• 由来する生物種: Saccharomyces cerevisiae (brewer's yeast); 詳細
• 細胞内の位置: Cytoplasm: A0A6L1BIF8 A0A6A5Q0W2 A0A6A5Q5W3 A0A6A5Q0P3 A0A8H8ULD3 P38624 A0A6A5PXC6 A0A6A5Q273 A0A6A5PXN2 A0A6A5PTH4 A0A6A5Q4M4 A0A6A5PYC9 A0A6A5Q449 A0A6L0YA22
• タンパク質・核酸の鎖数: 34
• 化学式量合計: 707744.57

構造登録者

Groll, M.,Hines, J.,Fahnestock, M.,Crews, M.C. (登録日: 2008-05-07, 公開日: 2008-06-10, 最終更新日: 2024-03-27)

• 主引用文献: Hines, J.,Groll, M.,Fahnestock, M.,Crews, C.M.; Proteasome Inhibition by Fellutamide B Induces Nerve Growth Factor Synthesis; Chem.Biol., 15:501-512, 2008; PubMed: 18482702; DOI: 10.1016/j.chembiol.2008.03.020

実験手法

X-RAY DIFFRACTION (2.6 Å)