3D1V
Crystal structure of human PNP complexed with 2-mercapto(3H) quinazolinone
Summary for 3D1V
Entry DOI | 10.2210/pdb3d1v/pdb |
Related | 1m73 1pf7 |
Descriptor | Purine nucleoside phosphorylase, SULFATE ION, 2-mercapto(3H)quinazolinone, ... (4 entities in total) |
Functional Keywords | purine nucleoside phosphorylase, drug design, synchrotron, empirical scoring function, 2-mercapto-4(3h) quinazolinone, acetylation, disease mutation, glycosyltransferase, polymorphism, transferase |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm, cytoskeleton (By similarity): P00491 |
Total number of polymer chains | 1 |
Total formula weight | 32651.28 |
Authors | De Azevedo Jr., W.F.,Basso, L.A.,Santos, D.S. (deposition date: 2008-05-06, release date: 2009-07-14, Last modification date: 2023-08-30) |
Primary citation | Timmers, L.F.,Caceres, R.A.,Vivan, A.L.,Gava, L.M.,Dias, R.,Ducati, R.G.,Basso, L.A.,Santos, D.S.,de Azevedo, W.F. Structural studies of human purine nucleoside phosphorylase: towards a new specific empirical scoring function Arch.Biochem.Biophys., 479:28-38, 2008 Cited by PubMed: 18790691DOI: 10.1016/j.abb.2008.08.015 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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