3D0L
Crystal structure of the HIV-1 broadly neutralizing antibody 2F5 in complex with the gp41 FP-MPER Hyb3K construct 514GIGALFLGFLGAAGS528KK-Ahx-655KNEQELLELDKWASLWN671
Summary for 3D0L
Entry DOI | 10.2210/pdb3d0l/pdb |
Related | 1TJH 2P8L 2P8M 2P8P 2PR4 3d0v |
Descriptor | 2F5 heavy chain, 2F5 light chain, Hyb3k peptide construct, ... (6 entities in total) |
Functional Keywords | hiv, antibody, neutralization, epitope, 2f5, gp41, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 52773.23 |
Authors | Bryson, S.,Julien, J.P.,Pai, E.F. (deposition date: 2008-05-01, release date: 2008-10-07, Last modification date: 2023-11-15) |
Primary citation | Julien, J.P.,Bryson, S.,Nieva, J.L.,Pai, E.F. Structural details of HIV-1 recognition by the broadly neutralizing monoclonal antibody 2F5: epitope conformation, antigen-recognition loop mobility, and anion-binding site. J.Mol.Biol., 384:377-392, 2008 Cited by PubMed: 18824005DOI: 10.1016/j.jmb.2008.09.024 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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