2PR4

Crystal Structure of Fab' from the HIV-1 Neutralizing Antibody 2F5

Summary for 2PR4

Entry DOI	10.2210/pdb2pr4/pdb
Related	2P8L 2P8M 2P8P
Descriptor	nmAb 2F5 Fab' Heavy Chain, nmAb 2F5 Fab' light Chain (3 entities in total)
Functional Keywords	nmab 2f5, gp41, hiv, viral protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	48365.28
Authors	Bryson, S.,Julien, J.-P.,Pai, E.F. (deposition date: 2007-05-03, release date: 2007-05-15, Last modification date: 2011-07-13)
Primary citation	Julien, J.P.,Bryson, S.,Nieva, J.L.,Pai, E.F. Structural details of HIV-1 recognition by the broadly neutralizing monoclonal antibody 2F5: epitope conformation, antigen-recognition loop mobility, and anion-binding site. J.Mol.Biol., 384:377-392, 2008 Cited by PubMed: 18824005 DOI: 10.1016/j.jmb.2008.09.024 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation