2P8P
Crystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 in complex with gp41 Peptide LELDKWASLW[N-Ac]
Summary for 2P8P
| Entry DOI | 10.2210/pdb2p8p/pdb |
| Related | 2P8L 2P8M |
| Descriptor | nmAb 2F5, light chain, nmAb 2F5, heavy chain, gp41 peptide, ... (4 entities in total) |
| Functional Keywords | nmab 2f5, hiv-1, gp41 epitope, viral protein |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 3 |
| Total formula weight | 49608.73 |
| Authors | Bryson, S.,Julien, J.-P.,Pai, E.F. (deposition date: 2007-03-22, release date: 2007-05-15, Last modification date: 2011-07-13) |
| Primary citation | Julien, J.P.,Bryson, S.,Nieva, J.L.,Pai, E.F. Structural details of HIV-1 recognition by the broadly neutralizing monoclonal antibody 2F5: epitope conformation, antigen-recognition loop mobility, and anion-binding site. J.Mol.Biol., 384:377-392, 2008 Cited by PubMed: 18824005DOI: 10.1016/j.jmb.2008.09.024 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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