3CWW
Crystal Structure of IDE-bradykinin complex
Summary for 3CWW
| Entry DOI | 10.2210/pdb3cww/pdb |
| Related | 2G47 2JG4 |
| Descriptor | Insulin-degrading enzyme, bradykinin N-terminal tetrapeptide analogue, ZINC ION, ... (6 entities in total) |
| Functional Keywords | a-beta degrading enzyme, criptidase, bradykinin, kinins, hydrolase |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: P14735 |
| Total number of polymer chains | 4 |
| Total formula weight | 229304.16 |
| Authors | Malito, E.,Tang, W.J. (deposition date: 2008-04-23, release date: 2008-11-25, Last modification date: 2023-08-30) |
| Primary citation | Malito, E.,Ralat, L.A.,Manolopoulou, M.,Tsay, J.L.,Wadlington, N.L.,Tang, W.J. Molecular Bases for the Recognition of Short Peptide Substrates and Cysteine-Directed Modifications of Human Insulin-Degrading Enzyme Biochemistry, 47:12822-12834, 2008 Cited by PubMed: 18986166DOI: 10.1021/bi801192h PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.96 Å) |
Structure validation
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