3CTR

Crystal structure of the RRM-domain of the poly(A)-specific ribonuclease PARN bound to m7GTP

3CTR の概要

• エントリーDOI: 10.2210/pdb3ctr/pdb
• 分子名称: Poly(A)-specific ribonuclease PARN, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE (3 entities in total)
• 機能のキーワード: parn, protein-rna-complex, m7g-cap, m7gtp, rna recognition motif, rrm, exonuclease, hydrolase, magnesium, metal-binding, nonsense-mediated mrna decay, nuclease, nucleus, phosphoprotein, rna-binding
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus : O95453
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 12360.39

構造登録者

Monecke, T.,Schell, S.,Dickmanns, A.,Ficner, R. (登録日: 2008-04-14, 公開日: 2008-07-29, 最終更新日: 2024-02-21)

• 主引用文献: Monecke, T.,Schell, S.,Dickmanns, A.,Ficner, R.; Crystal structure of the RRM domain of poly(A)-specific ribonuclease reveals a novel m(7)G-cap-binding mode.; J.Mol.Biol., 382:827-834, 2008; PubMed: 18694759; DOI: 10.1016/j.jmb.2008.07.073

実験手法

X-RAY DIFFRACTION (2.1 Å)