3CPO
Crystal structure of ketosteroid isomerase D40N with bound 2-fluorophenol
Summary for 3CPO
Entry DOI | 10.2210/pdb3cpo/pdb |
Descriptor | Delta(5)-3-ketosteroid isomerase, 2-fluorophenol (3 entities in total) |
Functional Keywords | enzyme, active site, hydrogen bond, geometry, isomerase, lipid metabolism, steroid metabolism |
Biological source | Pseudomonas putida |
Total number of polymer chains | 1 |
Total formula weight | 14659.62 |
Authors | Caaveiro, J.M.M.,Pybus, B.,Ringe, D.,Petsko, G. (deposition date: 2008-03-31, release date: 2008-09-23, Last modification date: 2023-08-30) |
Primary citation | Sigala, P.A.,Kraut, D.A.,Caaveiro, J.M.M.,Pybus, B.,Ruben, E.A.,Ringe, D.,Petsko, G.A.,Herschlag, D. Testing geometrical discrimination within an enzyme active site: constrained hydrogen bonding in the ketosteroid isomerase oxyanion hole J.Am.Chem.Soc., 130:13696-13708, 2008 Cited by PubMed: 18808119DOI: 10.1021/ja803928m PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.24 Å) |
Structure validation
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