3COV

Crystal Structure of Mycobacterium Tuberculosis Pantothenate Synthetase at 1.5 Ang resolution- apo form

3COV の概要

• エントリーDOI: 10.2210/pdb3cov/pdb
• 関連するPDBエントリー: 1MOP 1N2E 1N2H 2A7X 2A84 2A86 3COW 3COY 3COZ
• 分子名称: Pantothenate synthetase, SULFATE ION, GLYCEROL, ... (5 entities in total)
• 機能のキーワード: mycobacterium tuberculosis, pantothenate biosynthesis, enzymes, ligase, drug design, atp-binding, magnesium, metal-binding, nucleotide-binding
• 由来する生物種: Mycobacterium tuberculosis
• 細胞内の位置: Cytoplasm (Potential): P0A5R0
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 64125.32

構造登録者

Ciulli, A.,Chirgadze, D.Y.,Blundell, T.L.,Abell, C. (登録日: 2008-03-29, 公開日: 2008-10-07, 最終更新日: 2023-08-30)

• 主引用文献: Ciulli, A.,Scott, D.E.,Ando, M.,Reyes, F.,Saldanha, S.A.,Tuck, K.L.,Chirgadze, D.Y.,Blundell, T.L.,Abell, C.; Inhibition of Mycobacterium tuberculosis pantothenate synthetase by analogues of the reaction intermediate.; Chembiochem, 9:2606-2611, 2008; PubMed: 18821554; DOI: 10.1002/cbic.200800437

実験手法

X-RAY DIFFRACTION (1.5 Å)