3CL0

N1 Neuraminidase H274Y + oseltamivir

Summary for 3CL0

Entry DOI	10.2210/pdb3cl0/pdb
Related	3CKZ 3CL2
Descriptor	Neuraminidase, (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, CALCIUM ION, ... (4 entities in total)
Functional Keywords	n1, neuraminidase, h274y, oseltamivir, glycosidase, hydrolase, membrane, transmembrane, virion, viral protein
Biological source	Influenza A virus (A/Viet Nam/1203/2004(H5N1))
Total number of polymer chains	1
Total formula weight	42534.37
Authors	Collins, P.,Haire, L.F.,Lin, Y.P.,Liu, J.,Russell, R.J.,Walker, P.A.,Skehel, J.J.,Martin, S.R.,Hay, A.J.,Gamblin, S.J. (deposition date: 2008-03-18, release date: 2008-05-20, Last modification date: 2018-08-22)
Primary citation	Collins, P.J.,Haire, L.F.,Lin, Y.P.,Liu, J.,Russell, R.J.,Walker, P.A.,Skehel, J.J.,Martin, S.R.,Hay, A.J.,Gamblin, S.J. Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants. Nature, 453:1258-1261, 2008 Cited by PubMed: 18480754 DOI: 10.1038/nature06956 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation