3CKD

Crystal structure of the C-terminal domain of the Shigella type III effector IpaH

Summary for 3CKD

Entry DOI	10.2210/pdb3ckd/pdb
Descriptor	Invasion plasmid antigen, secreted by the Mxi-Spa secretion machinery, SULFATE ION, GLYCEROL, ... (5 entities in total)
Functional Keywords	e3 ubiquitin ligase, helical, type iii effector, structural genomics, psi-2, protein structure initiative, midwest center for structural genomics, mcsg, ligase
Biological source	Shigella flexneri 2a str. 301
Total number of polymer chains	3
Total formula weight	107498.46
Authors	Lam, R.,Singer, A.U.,Cuff, M.E.,Skarina, T.,Kagan, O.,DiLeo, R.,Edwards, A.M.,Joachimiak, A.,Savchenko, A.,Midwest Center for Structural Genomics (MCSG) (deposition date: 2008-03-14, release date: 2008-03-25, Last modification date: 2011-07-13)
Primary citation	Singer, A.U.,Rohde, J.R.,Lam, R.,Skarina, T.,Kagan, O.,Dileo, R.,Chirgadze, N.Y.,Cuff, M.E.,Joachimiak, A.,Tyers, M.,Sansonetti, P.J.,Parsot, C.,Savchenko, A. Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases. Nat.Struct.Mol.Biol., 15:1293-1301, 2008 Cited by PubMed: 18997778 DOI: 10.1038/nsmb.1511 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.65 Å)

Structure validation