3CIK
Human GRK2 in Complex with Gbetagamma subunits
3CIK の概要
エントリーDOI | 10.2210/pdb3cik/pdb |
関連するPDBエントリー | 1BX6 1OMW 3CIL |
分子名称 | Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (5 entities in total) |
機能のキーワード | protein kinase, complex, g protein, receptor, wd40 repeat, atp-binding, nucleotide-binding, serine/threonine-protein kinase, transferase, transducer, wd repeat, lipoprotein, membrane, phosphoprotein, prenylation, transferase-signaling protein complex, transferase/signaling protein |
由来する生物種 | Homo sapiens (Human) 詳細 |
細胞内の位置 | Cell membrane; Lipid-anchor; Cytoplasmic side (Potential): P63212 |
タンパク質・核酸の鎖数 | 3 |
化学式量合計 | 125540.53 |
構造登録者 | |
主引用文献 | Tesmer, J.J.,Tesmer, V.M.,Lodowski, D.T.,Steinhagen, H.,Huber, J. Structure of human G protein-coupled receptor kinase 2 in complex with the kinase inhibitor balanol. J.Med.Chem., 53:1867-1870, 2010 Cited by PubMed: 20128603DOI: 10.1021/jm9017515 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.75 Å) |
構造検証レポート
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