3CIK

Human GRK2 in Complex with Gbetagamma subunits

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Beta-adrenergic receptor kinase 1	polymer	689	79692.6	1	UniProt (P25098) Pfam (PF00615) Pfam (PF00069) Pfam (PF00169) In PDB	Homo sapiens (Human)	Beta-ARK-1, G-protein coupled receptor kinase 2
2	B	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	polymer	340	37416.9	1	UniProt (P62871) Pfam (PF00400) In PDB	Bos taurus (Bovine)	Transducin beta chain 1
3	G	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2	polymer	74	8406.7	1	UniProt (P63212) Pfam (PF00631) In PDB	Bos taurus (Bovine)	G gamma-I
4	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
5		water	water		18.0	19	Chemie (HOH)

Sequence modifications

G: 1 - 68 (UniProt: P63212)

PDB	External Database	Details
His -5	-	EXPRESSION TAG
His -4	-	EXPRESSION TAG
His -3	-	EXPRESSION TAG
His -2	-	EXPRESSION TAG
His -1	-	EXPRESSION TAG
His 0	-	EXPRESSION TAG

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	125516.2
Non-Polymers*	Number of molecules	1
	Total formula weight	24.3
All*	Total formula weight	125540.5

*Water molecules are not included.