3CF6
Structure of Epac2 in complex with cyclic-AMP and Rap
Summary for 3CF6
Entry DOI | 10.2210/pdb3cf6/pdb |
Related | 2BYV |
Descriptor | Rap guanine nucleotide exchange factor (GEF) 4, Ras-related protein Rap-1b, 6-(6-AMINO-PURIN-9-YL)-2-THIOXO-TETRAHYDRO-2-FURO[3,2-D][1,3,2]DIOXAPHOSPHININE-2,7-DIOL, ... (5 entities in total) |
Functional Keywords | epac, rapgef4, rap, rap1b, camp, sp-camps, gef, gunanine nucleotide exchange factor, g-protein, gtp-binding, nucleotide-binding, signaling protein regulator-gtp-binding protein complex, signaling protein-gtp-binding protein complex, signaling protein/gtp-binding protein |
Biological source | Mus musculus (mouse) More |
Cellular location | Cell membrane: P61224 |
Total number of polymer chains | 2 |
Total formula weight | 99084.95 |
Authors | Rehmann, H.,Arias-Palomo, E.,Hadders, M.A.,Schwede, F.,Llorca, O.,Bos, J.L. (deposition date: 2008-03-02, release date: 2008-07-29, Last modification date: 2023-11-01) |
Primary citation | Rehmann, H.,Arias-Palomo, E.,Hadders, M.A.,Schwede, F.,Llorca, O.,Bos, J.L. Structure of Epac2 in complex with a cyclic AMP analogue and RAP1B Nature, 455:124-127, 2008 Cited by PubMed: 18660803DOI: 10.1038/nature07187 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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