3CBB

Crystal Structure of Hepatocyte Nuclear Factor 4alpha in complex with DNA: Diabetes Gene Product

3CBB の概要

• エントリーDOI: 10.2210/pdb3cbb/pdb
• 分子名称: Hepatocyte Nuclear Factor 4-alpha promoter element DNA, Hepatocyte Nuclear Factor 4-alpha, DNA binding domain, ZINC ION, ... (5 entities in total)
• 機能のキーワード: zinc finger, protein-dna complex, diabetes, transcription-dna complex, transcription/dna
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus: P41235
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 31260.15

構造登録者

Lu, P.,Rha, G.B.,Melikishvili, M.,Adkins, B.C.,Fried, M.G.,Chi, Y.I. (登録日: 2008-02-21, 公開日: 2008-10-07, 最終更新日: 2024-02-21)

• 主引用文献: Lu, P.,Rha, G.B.,Melikishvili, M.,Wu, G.,Adkins, B.C.,Fried, M.G.,Chi, Y.I.; Structural basis of natural promoter recognition by a unique nuclear receptor, HNF4alpha. Diabetes gene product.; J.Biol.Chem., 283:33685-33697, 2008; PubMed: 18829458; DOI: 10.1074/jbc.M806213200

実験手法

X-RAY DIFFRACTION (2 Å)