3C5G
Structure of a ternary complex of the R517K Pol lambda mutant
Summary for 3C5G
Entry DOI | 10.2210/pdb3c5g/pdb |
Related | 3C5F |
Descriptor | DNA polymerase lambda, DNA (5'-D(*DCP*DGP*DGP*DCP*DAP*DAP*DTP*DAP*DCP*DTP*DG)-3'), DNA (5'-D(*DCP*DAP*DGP*DTP*DAP*(2DT))-3'), ... (9 entities in total) |
Functional Keywords | helix-hairpin-helix, dna damage, dna repair, dna replication, dna synthesis, dna-binding, dna-directed dna polymerase, lyase, manganese, metal-binding, nucleotidyltransferase, nucleus, phosphoprotein, transferase, transferase/dna, lyase-dna complex, transferase-dna, lyase/dna |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus : Q9UGP5 |
Total number of polymer chains | 8 |
Total formula weight | 88814.92 |
Authors | Garcia-Diaz, M.,Bebenek, K.,Foley, M.C.,Pedersen, L.C.,Schlick, T.,Kunkel, T.A. (deposition date: 2008-01-31, release date: 2008-07-29, Last modification date: 2024-10-09) |
Primary citation | Bebenek, K.,Garcia-Diaz, M.,Foley, M.C.,Pedersen, L.C.,Schlick, T.,Kunkel, T.A. Substrate-induced DNA strand misalignment during catalytic cycling by DNA polymerase lambda. Embo Rep., 9:459-464, 2008 Cited by PubMed: 18369368DOI: 10.1038/embor.2008.33 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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