3C57

Crystal Structure of the Mycobacterium tuberculosis Hypoxic Response Regulator DosR C-terminal Domain Crystal Form II

Summary for 3C57

Entry DOI	10.2210/pdb3c57/pdb
Related	1zlj 1zlk 3C3W
Descriptor	TWO COMPONENT TRANSCRIPTIONAL REGULATORY PROTEIN DEVR (2 entities in total)
Functional Keywords	response regulator, two-component regulatory system, dna-binding protein, tuberculosis, transcription regulation, transcription
Biological source	Mycobacterium tuberculosis
Cellular location	Cytoplasm (Probable): P95193
Total number of polymer chains	2
Total formula weight	21028.00
Authors	Wisedchaisri, G.,Wu, M.,Sherman, D.R.,Hol, W.G.J. (deposition date: 2008-01-30, release date: 2008-04-22, Last modification date: 2023-08-30)
Primary citation	Wisedchaisri, G.,Wu, M.,Sherman, D.R.,Hol, W.G. Crystal structures of the response regulator DosR from Mycobacterium tuberculosis suggest a helix rearrangement mechanism for phosphorylation activation J.Mol.Biol., 378:227-242, 2008 Cited by PubMed: 18353359 DOI: 10.1016/j.jmb.2008.02.029 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation