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3C4T

Structure of RNaseIIIb and dsRNA binding domains of mouse Dicer

Summary for 3C4T
Entry DOI10.2210/pdb3c4t/pdb
Related3C4B
DescriptorEndoribonuclease Dicer, CADMIUM ION (3 entities in total)
Functional Keywordsrnase, atp-binding, endonuclease, helicase, hydrolase, nuclease, nucleotide-binding, phosphoprotein, rna-binding, rna-mediated gene silencing
Biological sourceMus musculus (house mouse)
Cellular locationCytoplasm (By similarity): Q8R418
Total number of polymer chains1
Total formula weight30933.99
Authors
Lee, J.K.,Du, Z.,Tjhen, R.J.,Stroud, R.M.,James, T.L. (deposition date: 2008-01-30, release date: 2008-02-19, Last modification date: 2011-07-13)
Primary citationDu, Z.,Lee, J.K.,Tjhen, R.,Stroud, R.M.,James, T.L.
Structural and biochemical insights into the dicing mechanism of mouse Dicer: A conserved lysine is critical for dsRNA cleavage.
Proc.Natl.Acad.Sci.Usa, 105:2391-2396, 2008
Cited by
PubMed: 18268334
DOI: 10.1073/pnas.0711506105
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.8 Å)
Structure validation

217705

數據於2024-03-27公開中

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