3C4T

Structure of RNaseIIIb and dsRNA binding domains of mouse Dicer

3C4T の概要

• エントリーDOI: 10.2210/pdb3c4t/pdb
• 関連するPDBエントリー: 3C4B
• 分子名称: Endoribonuclease Dicer, CADMIUM ION (3 entities in total)
• 機能のキーワード: rnase, atp-binding, endonuclease, helicase, hydrolase, nuclease, nucleotide-binding, phosphoprotein, rna-binding, rna-mediated gene silencing
• 由来する生物種: Mus musculus (house mouse)
• 細胞内の位置: Cytoplasm (By similarity): Q8R418
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 30933.99

構造登録者

Lee, J.K.,Du, Z.,Tjhen, R.J.,Stroud, R.M.,James, T.L. (登録日: 2008-01-30, 公開日: 2008-02-19, 最終更新日: 2011-07-13)

• 主引用文献: Du, Z.,Lee, J.K.,Tjhen, R.,Stroud, R.M.,James, T.L.; Structural and biochemical insights into the dicing mechanism of mouse Dicer: A conserved lysine is critical for dsRNA cleavage.; Proc.Natl.Acad.Sci.Usa, 105:2391-2396, 2008; PubMed: 18268334; DOI: 10.1073/pnas.0711506105

実験手法

X-RAY DIFFRACTION (2.8 Å)