3BVH

Crystal Structure of Recombinant gammaD364A Fibrinogen Fragment D with the Peptide Ligand Gly-Pro-Arg-Pro-Amide

Summary for 3BVH

Entry DOI	10.2210/pdb3bvh/pdb
Related	1FZA 1LT9 1LTJ
Descriptor	Fibrinogen alpha chain, Fibrinogen beta chain, Fibrinogen gamma chain, ... (7 entities in total)
Functional Keywords	blood clotting, blood coagulation, disease mutation, glycoprotein, phosphoprotein, secreted, pyrrolidone carboxylic acid, sulfation
Biological source	Homo sapiens (human) More
Total number of polymer chains	10
Total formula weight	152490.87
Authors	Bowley, S.R.,Merenbloom, B.K.,Betts, L.,Okumura, N.,Heroux, A.,Gorkun, O.V.,Lord, S.T. (deposition date: 2008-01-07, release date: 2008-09-02, Last modification date: 2023-08-30)
Primary citation	Bowley, S.R.,Merenbloom, B.K.,Okumura, N.,Betts, L.,Heroux, A.,Gorkun, O.V.,Lord, S.T. Polymerization-defective fibrinogen variant gammaD364A binds knob "A" peptide mimic. Biochemistry, 47:8607-8613, 2008 Cited by PubMed: 18642883 DOI: 10.1021/bi8000769 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation