3BU8
Crystal Structure of TRF2 TRFH domain and TIN2 peptide complex
Summary for 3BU8
Entry DOI | 10.2210/pdb3bu8/pdb |
Related | 3BQO 3BUA |
Descriptor | Telomeric repeat-binding factor 2, TERF1-interacting nuclear factor 2 (3 entities in total) |
Functional Keywords | trf2 trfh domain trf2 dimerization domain tin2 peptide, alternative splicing, cell cycle, chromosomal protein, dna-binding, nucleus, phosphoprotein, telomere, dna binding protein |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: Q15554 Nucleus. Isoform 1: Nucleus matrix: Q9BSI4 |
Total number of polymer chains | 4 |
Total formula weight | 58269.28 |
Authors | Chen, Y.,Yang, Y.,van Overbeek, M.,Donigian, J.R.,Baciu, P.,de Lange, T.,Lei, M. (deposition date: 2008-01-02, release date: 2008-02-19, Last modification date: 2023-08-30) |
Primary citation | Chen, Y.,Yang, Y.,van Overbeek, M.,Donigian, J.R.,Baciu, P.,de Lange, T.,Lei, M. A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins. Science, 319:1092-1096, 2008 Cited by PubMed: 18202258DOI: 10.1126/science.1151804 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
Download full validation report