3BRH

Protein Tyrosine Phosphatase PTPN-22 (Lyp) bound to the mono-Phosphorylated Lck active site peptide

3BRH の概要

• エントリーDOI: 10.2210/pdb3brh/pdb
• 分子名称: Tyrosine-protein phosphatase non-receptor type 22, Lck Active Site Peptide, PHOSPHATE ION, ... (4 entities in total)
• 機能のキーワード: lyp, ptpn22, phosphatase, lck, alternative splicing, cytoplasm, hydrolase, polymorphism, protein phosphatase, systemic lupus erythematosus
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Cytoplasm : Q9Y2R2
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 74719.07

構造登録者

Seidel, R.D.,Love, J.,Piserchio, A.,Cowburn, D. (登録日: 2007-12-21, 公開日: 2009-02-17, 最終更新日: 2024-02-21)

• 主引用文献: Seidel, R.,Love, J.,Piserchio, A.,Cowburn, D.; Lyp/PTPN22 Phosphatase Domain: Substrate Recognition and Specificity for Src family kinases; To be Published,

実験手法

X-RAY DIFFRACTION (2.2 Å)