3BRD

CSL (Lag-1) bound to DNA with Lin-12 RAM peptide, P212121

Summary for 3BRD

• Entry DOI: 10.2210/pdb3brd/pdb
• Related: 3BRF 3BRG
• Descriptor: DNA (5'-D(*DTP*DTP*DAP*DCP*DTP*DGP*DTP*DGP*DGP*DGP*DAP*DAP*DAP*DGP*DA)-3'), DNA (5'-D(*DAP*DAP*DTP*DCP*DTP*DTP*DTP*DCP*DCP*DCP*DAP*DCP*DAP*DGP*DT)-3'), Lin-12 and glp-1 phenotype protein 1, isoform a, ... (6 entities in total)
• Functional Keywords: protein-dna complex, signaling, transcription, notch, dna-binding, ank repeat, developmental protein, differentiation, egf-like domain, glycoprotein, membrane, transmembrane, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Caenorhabditis elegans; More
• Cellular location: Membrane; Single-pass type I membrane protein: P14585
• Total number of polymer chains: 4
• Total formula weight: 67081.42

Authors

Wilson, J.J.,Kovall, R.A. (deposition date: 2007-12-21, release date: 2008-04-01, Last modification date: 2024-02-21)

• Primary citation: Friedmann, D.R.,Wilson, J.J.,Kovall, R.A.; RAM-induced Allostery Facilitates Assembly of a Notch Pathway Active Transcription Complex.; J.Biol.Chem., 283:14781-14791, 2008; PubMed: 18381292; DOI: 10.1074/jbc.M709501200

Experimental method

X-RAY DIFFRACTION (2.21 Å)