3BRD

CSL (Lag-1) bound to DNA with Lin-12 RAM peptide, P212121

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000978	molecular_function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
A	0001228	molecular_function	DNA-binding transcription activator activity, RNA polymerase II-specific
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0005634	cellular_component	nucleus
A	0006355	biological_process	regulation of DNA-templated transcription
A	0006357	biological_process	regulation of transcription by RNA polymerase II

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO A 1

Chain	Residue
A	PHE220
A	CYS241
A	TYR243
A	TRP422
A	ALA424
A	HOH757
A	HOH760

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site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 2

Chain	Residue
A	ARG631
A	THR629
A	ASN630

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 3

Chain	Residue
A	GLU545
A	ARG547
A	SER651
A	GLY653

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site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 4

Chain	Residue
A	GLN361
A	LYS543
A	ALA544
A	GLU545

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 5

Chain	Residue
A	GLN300
A	GLN301
A	ALA326
A	ALA327
A	LYS328
A	THR329

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site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO D 6

Chain	Residue
A	THR462
A	GLY463
A	ILE464
D	ALA942
D	SER943

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site_id	AC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE EDO C 16

Chain	Residue
C	DT6

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site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 8

Chain	Residue
A	TYR289
A	PHE348

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site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 9

Chain	Residue
A	LEU207
A	MET627
A	PHE628
A	PRO639

---

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 10

Chain	Residue
A	ARG445
A	PHE448
A	GLU580
A	ARG604
A	HOH699

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