3BO8
The High Resolution Crystal Structure of HLA-A1 Complexed with the MAGE-A1 Peptide
Summary for 3BO8
Entry DOI | 10.2210/pdb3bo8/pdb |
Related | 1W72 |
Descriptor | HLA class I histocompatibility antigen, A-1 alpha chain, Beta-2-microglobulin, nonameric peptide from Melanoma-associated antigen 1, ... (5 entities in total) |
Functional Keywords | melanoma associated antigen, mage, mage-a1, major histocompatibility complex, mhc, human leukocyte antigen, hla, hla-a1, hla-a010101, tcr, t-cell receptor, antibody, fab-hyb3, hyb3, glycoprotein, host-virus interaction, immune response, immunoglobulin domain, membrane, mhc i, sulfation, transmembrane, disease mutation, glycation, pyrrolidone carboxylic acid, secreted, tumor antigen, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P30443 Secreted: P61769 Cytoplasm: P43355 |
Total number of polymer chains | 3 |
Total formula weight | 44769.56 |
Authors | Kumar, P.,Vahedi-Faridi, A.,Saenger, W.,Ziegler, A.,Uchanska-Ziegler, B. (deposition date: 2007-12-17, release date: 2008-12-23, Last modification date: 2023-11-01) |
Primary citation | Kumar, P.,Vahedi-Faridi, A.,Saenger, W.,Ziegler, A.,Uchanska-Ziegler, B. Conformational changes within the HLA-A1:MAGE-A1 complex induced by binding of a recombinant antibody fragment with TCR-like specificity Protein Sci., 18:37-49, 2009 Cited by PubMed: 19177349DOI: 10.1002/pro.4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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